At Tyres.co.uk, the Mercedes E53 AMG options include the 245/40 ZR19 98Y XL front and 275/35 ZR19 100Y XL rear (E 53 4MATIC+ Saloons) 2018-2023 models fitted with 19-inch AMG wheels. You should check the registration, load index, and speed rating before purchase.
The Mercedes E53 AMG tyre size is displayed within the tyre size placard within the fuel filler flap. The placard displays the authorised fitments for wheels and tyres. You should check against the tyre sidewall and owner's manual before placing your order for tyres.
While it is not necessary to purchase four new tyres for the Mercedes E53 AMG, due to its 4MATIC+ drivetrain, you are required to maintain the front and rear fitment as well as the same tyre type and brand. You should purchase all four if you cannot maintain the same type and brand. According to UK tyre safety guidelines, you should put two new tyres on the rear axle.