Tyres.co.uk lists Michelin Pilot Sport 5 and Pirelli P Zero (PZ4) tyres in 245/40 R19 98Y XL front and 275/35 R19 100Y XL rear sizes for the 2018 Mercedes CLS-Class CLS 350 D on the staggered 19-inch factory wheels. Note that before ordering tyres you must confirm the registration, load index, speed rating, and specifications.
For the CLS-Class, the tyre pressure and corresponding sizes are listed on the tyre pressure warning sticker in the fuel filler flap. The factory recommends these sizes and pressures. For the 2018 CLS-Class, the driver side B-post is also listed with a Tyre and Loading Information sticker. Since the optional wheels differ across the various trim levels of the CLS-Class, it is recommended that you check the current tyre sidewalls and registration.
All four Mercedes CLS-Class tyres do not have to be replaced at once, though tyres of the same size should be replaced together and the same make and type kept across each axle. 4MATIC versions do not force a four-tyre replacement on their own, but need the closest match that can be maintained. Where two tyres are replaced, fit the new pair to the rear axle.