At Tyres.co.uk, Audi S8 options include Michelin Pilot Sport 4 S and Pirelli P Zero (PZ4) in 265/35 R21 101Y XL for the D5 S8 models with 21-inch factory wheels. Make sure to confirm the tyre-pressure label and your registration to make an order. Different specifications may apply to other generation S8 models or different factory wheel options.
The tyre size for the Audi S8 is listed on the tyre-pressure placard located on the driver's side door as the driver door is opened. The placard outlines the specifications for approved wheel and tyre combinations along with the load and speed ratings and each tyre's recommended pressure. Answer the information on the placard in reference to your front registered tyres, as there are variations to factory fitments of the S8 of different generations and wheel options.
With the Audi S8 having quattro four wheel drive, the brand and construction of all four tyres should be the same, as should the size and rolling circumference, and the tread pattern should be the same. Tyre replacements do not always have to be done in sets, but if some cannot be replaced in sets, all four tyres have to be replaced. Based on UK tyre safety guidelines, if two new tyres are fitted, they should be placed on the rear axle.