It can, but you should confirm the exact size and load rating listed on the vehicle door placard or in the handbook first. 265/75 R16 is a taller overall diameter than many common alternatives, so check for clearance on full steering lock and under suspension compression, especially if the vehicle is unmodified. If your vehicle currently runs a different size, changeovers can also affect speedometer accuracy and gearing.
265 is the tyre width in millimetres, 75 is the aspect ratio (sidewall height as a percentage of the width), R means radial construction, and 16 is the wheel diameter in inches. Because the 75 profile is relatively tall, this size is often chosen for tougher use on pickups and 4x4s where sidewall flex and impact resistance are useful.
Choose LT (Light Truck) if you regularly carry heavy loads, tow, or drive on rougher surfaces where stronger carcass construction helps. Many 265/75 R16 LT tyres come with higher load indices (often in the 120+ range) compared with passenger-rated versions, but the ride can be firmer. Match the load index and any ply rating marking to your vehicle requirements, not just the tread pattern.
For mainly tarmac use, a road pattern in 265/75 R16 is typically quieter and can deliver better wet braking. If you split time between lanes, gravel, fields and work sites, an all-terrain is usually the best balance of grip and wear. Mud-terrain options suit frequent deep mud and rutted tracks, but they tend to be louder and can wear faster on road.
Avoid mixing sizes, especially on permanent 4WD and AWD systems, because different rolling circumferences can strain the drivetrain. Keep the same size, load index and similar tread depth across an axle at minimum, and ideally replace all four together. If you are upgrading or changing away from 265/75 R16, do it as a complete set and check the spare wheel size too.